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Joachim H C Orth Selected Research

Pasteurella multocida toxin

10/2019Activation of Gq signaling by Pasteurella multocida toxin inhibits the osteoblastogenic-like actions of Activin A in C2C12 myoblasts, a cell model of fibrodysplasia ossificans progressiva.
1/2018Involvement of Osteocytes in the Action of Pasteurella multocida Toxin.
9/2015A systemic Pasteurella multocida toxin aggravates cardiac hypertrophy and fibrosis in mice.
11/2014Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin.
7/2013Pasteurella multocida toxin as a transporter of non-cell-permeating proteins.
1/2012Molecular biology of Pasteurella multocida toxin.
4/2009Pasteurella multocida toxin activation of heterotrimeric G proteins by deamidation.

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Joachim H C Orth Research Topics

Disease

7Atrophic Rhinitis (Ozena)
01/2018 - 04/2009
3Neoplasms (Cancer)
11/2014 - 02/2007
2Infections
11/2005 - 08/2004
1Myositis Ossificans (Fibrodysplasia Ossificans Progressiva)
10/2019
1Fibrosis (Cirrhosis)
09/2015
1Cardiomegaly (Heart Hypertrophy)
09/2015
1Hypertrophy
09/2015
1Bone Resorption
11/2014
1Atrophy
07/2013
1Bites and Stings (Sting)
02/2013
1Wounds and Injuries (Trauma)
02/2013
1Leukemia
07/2010
1Pasteurella Infections (Pasteurellosis)
04/2009

Drug/Important Bio-Agent (IBA)

7Pasteurella multocida toxinIBA
10/2019 - 04/2009
4Proteins (Proteins, Gene)FDA Link
10/2019 - 07/2013
2Virulence Factors (Pathogenicity Factors)IBA
02/2013 - 04/2009
2Heterotrimeric GTP-Binding Proteins (Heterotrimeric G-Proteins)IBA
01/2013 - 08/2010
1activin AIBA
10/2019
1Mitogen-Activated Protein KinasesIBA
09/2015
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
09/2015
1Phosphotransferases (Kinase)IBA
09/2015
1GTP-Binding Proteins (G-Protein)IBA
11/2014
1Tartrate-Resistant Acid PhosphataseIBA
11/2014
1Bacterial ToxinsIBA
01/2013
1GTP Phosphohydrolases (GTPases)IBA
07/2010
12,6-dinitrotoluene (DNT)IBA
07/2010
1Bordetella dermonecrotic toxinIBA
07/2010
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
02/2007
1LuciferasesIBA
11/2005
1YM-254890IBA
11/2005
1Phospholipases (Phospholipase)IBA
08/2004